Efetov, Pépin, and Meier Reply:

Kaplan–Meier Estimator

The Kaplan–Meier estimator is a nonparametric estimator which may be used to estimate the survival distribution function from censored data. The estimator may be obtained as the limiting case of the classical actuarial (life table) estimator, and it seems to have been first proposed by Böhmer [2]. It was, however, lost sight of by later researchers and not investigated further until the importa...

Meier-Gorlin syndrome

Meier-Gorlin syndrome (MGS) is a rare autosomal recessive primordial dwarfism disorder, characterized by microtia, patellar applasia/hypoplasia, and a proportionate short stature. Associated clinical features encompass feeding problems, congenital pulmonary emphysema, mammary hypoplasia in females and urogenital anomalies, such as cryptorchidism and hypoplastic labia minora and majora. Typical ...

The Authors’ Reply

The Authors’ Reply

About an adaptively weighted Kaplan-Meier estimate.

The minimum averaged mean squared error nonparametric adaptive weights use data from m possibly different populations to infer about one population of interest. The definition of these weights is based on the properties of the empirical distribution function. We use the Kaplan-Meier estimate to let the weights accommodate right-censored data and use them to define the weighted Kaplan-Meier esti...